Sangamo BioSciences Initiates Phase 2 Clinical Trial of Treatment for Amyotrophic Lateral Sclerosis (ALS)

Press Release  |  www.prnewswire.com | Sep 3, 2008

Sangamo's drug, SB-509, is an injectable formulation of a plasmid encoding a zinc finger DNA-binding protein transcription factor (ZFP TF(TM)) designed to upregulate the expression of the gene encoding vascular endothelial growth factor (VEGF-A).

http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=109&STORY=/www/story/09-03-2008/0004877509&EDATE=

New drug for melanoma riluzole shows promise

News  |  www.news-medical.net | Apr 17, 2008

Rutgers Professor Suzie Chen has found that riluzole, a U.S. Food and Drug Administration (FDA) approved drug used to treat Lou Gehrig's disease (ALS), slows the growth of melanoma, the most aggressive form of malignant skin cancer. Rutgers Professor Suzie Chen has found that riluzole, a U.S. Food

http://www.news-medical.net/?id=37423

MedlinePlus Medical Encyclopedia: Amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis, or ALS, is a disease of the nerve cells in the brain and spinal cord that are responsible for voluntary muscle movement. ALS is also known as Lou Gehrig's disease.

http://www.nlm.nih.gov/medlineplus/ency/article/000688.htm

HON - News : Study Shows Antibiotic Harms ALS Patients

THURSDAY, Nov. 1 (HealthDay News) -- A trial of the antibiotic minocycline against amyotrophic lateral sclerosis -- Lou Gehrig's disease -- has been halted because patients taking the drug had a significantly accelerated decline in neurological function.

http://www.hon.ch/News/HSN/609630.html

The Johns Hopkins Psychiatry Newsletter

Two summers ago, John Helliwell rounded up his pill bottles, the remains of a dozen or so medications supposed to dispel the depression that had cycled relentlessly in and out of his life for years. He’d been 12 the first time he tried suicide.

http://www.hopkinsmedicine.org/Psychiatry/newsletter/06_winter/riluzole_bipolar.html

australiandoctor.com.au

News  |  www.australiandoctor.com.au

By Michael Woodhead RILUZOLE (Rilutek), a drug that may slow the progression of motor neurone disease and prolong survival by up to nine months, will soon be available on the PBS, neurologists say.

http://www.australiandoctor.com.au/news/ba/0c016eba.asp

1995.12.12: FDA Approves First Drug for Lou Gehrig's Disease

The Food and Drug Administration today announced the approval of riluzole, the first drug that has been shown to prolong the survival of patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.

http://www.hhs.gov/news/press/1995pres/951212.html

HON - News : Drug Proves Effective in Slowing Melanomas

TUESDAY, April 15 (HealthDay News) -- The drug riluzole, approved in the United States to treat amyotrophic lateral sclerosis (ALS), slows the growth of highly aggressive melanoma skin cancer, according to a new study.

http://www.hon.ch/News/HSN/614557.html