About Inspire

Inspire is a biopharmaceutical company dedicated to discovering, developing and commercializing prescription pharmaceutical products in disease areas with significant commercial potential and unmet medical needs. Inspire employs a U.S. sales force for the promotion of AzaSite(R) (azithromycin ophthalmic solution) 1% for bacterial conjunctivitis, Elestat(R) (epinastine HCl ophthalmic solution) 0.05% for allergic conjunctivitis and Restasis(R) (cyclosporine ophthalmic emulsion) 0.05% for dry eye. Inspire is focused on the therapeutic areas of ophthalmology and respiratory, and is developing products for dry eye, cystic fibrosis and glaucoma. Elestat and Restasis are registered trademarks owned by Allergan, Inc. AzaSite is a registered trademark owned by InSite Vision Incorporated. For more information, visit www.inspirepharm.com.

SOURCE: Inspire Pharmaceuticals, Inc.

Investor Contact:
Inspire Pharmaceuticals, Inc.
Jenny Kobin, 919-941-9777, ext. 219
VP, Investor Relations and Corporate Communications
or
Media Contact:
BMC Communications
Dan Budwick, 212-477-9007, ext. 14

Blanco, a native of Argentina, has more than 20 years of emerging markets experience. He joined Deutsche Bank in New York in 2000 and was appointed Head of Debt Capital Markets for Latin America in 2003. In 2006, he was appointed Head of Corporate & Client Coverage for Latin America, responsible for overseeing all corporate, sovereign and institutional coverage for the region.

Hinsley, who was most recently responsible for Emerging Markets structured liability origination, joined Deutsche Bank in London in 1999. He was responsible for the Debt Capital Markets coverage of Deutsche Bank's Supra-National and Sovereign clients, and later became Global Head of Euro medium term note trading and origination.

Caputo has had a distinguished banking career both in Argentina and internationally. He joined Deutsche Bank in 1997 as Global Head of Emerging Markets Fixed Income Trading. In 1999, he moved to Deutsche Bank S.A. Argentina and took on the role of Head of Global Markets Argentina. In 2003, he was appointed President and CEO of Deutsche Bank S.A. Argentina.

"Our success in Argentina despite challenging markets is a testament to Luis' leadership, and we sincerely thank him for everything he has done for the firm," said Waugh. "We are also confident that Marcelo is ideally suited to lead our business in Argentina going forward and will ensure a seamless transition for Deutsche Bank and our clients."

"Marcelo's client relationships and track record of success have made him an invaluable part of our Latin American franchise," said Ariburnu. "His understanding of the market and outstanding reputation in the region will enable us to continue building our successful business in Argentina."

Blanco earned BS and MS degrees in Industrial Engineering from Instituto Tecnologico Buenos Aires in Argentina and an MA from the University of California, Santa Barbara.

Hinsley graduated with a bachelor's degree in political science from the University of New Hampshire and earned an MBA in Finance from New York University's Stern School of Business.

About Deutsche Bank

Deutsche Bank (NYSE: DB) is a leading global investment bank with a strong and profitable private clients franchise. A leader in Germany and Europe, the bank is continuously growing in North America, Asia and key emerging markets. With 78,291 employees in 76 countries, Deutsche Bank competes to be the leading global provider of financial solutions for demanding clients creating exceptional value for its shareholders and people.

Deutsche Bank Securities Inc., member NYSE, FINRA and SIPC, is the investment banking and securities arm of Deutsche Bank AG in the United States.

www.db.com

SOURCE: Deutsche Bank

Deutsche Bank
Michele Allison, +1 212-250-4864
Ted Meyer, +1 212-250-7253

"Pratik has a deep understanding of the Asian equities markets and his appointment will assist Deutsche Bank in consolidating our dominant position in the institutional equities space," bank's Managing Director and CEO Gunit Chadha said in the release.

Gupta will report to Pavan Sukhdev, Head, Global Markets, in India and regionally to Noreddine Sebti, Head Global Markets Equity-Asia.

Deutsche Bank said the company has moved aggressively to cut costs at its Shoppers unit, which delivers color circulars by mail throughout California and South Florida.

It said costs are down 14% in the first quarter compared to the same period a year ago and it expects the company to continue paring back significantly due to the economic weakness of its West Coast markets.

Deutsche Bank said the sharp year-over-year declines in Shoppers' earnings before interest tax depreciation and amortization probably peaked in the first quarter. Cost cutting should now see those declines lessen.

The broker said analysts are clearly factoring in a second-half slowdown in direct marketing demand. At the same time, Deutsche Bank said Harte-Hanks' direct marketing should still manage revenue growth of 2% in the last six months of the year.

It maintained a price target of $12.

The broker's upgrade comes a day after the company posted a 33% drop in first-quarter net income to $25.8 million.

mark.cotton@thomsonreuters.com mc1/vj

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