William Blair & Company is acting as the sole book running manager and Barrington Research Associates, Inc. is acting as co-manager for the offering.

The public offering is being made only by means of a prospectus, copies of which may be obtained, when available, from:

 William Blair & Company, L.L.C.
 Attention: Prospectus Department
 222 West Adams
 Chicago, Illinois 60606
 Telephone: 800-621-0687

A registration statement (including a prospectus) relating to the offering to which this communication relates has been filed with the Securities and Exchange Commission, but has not yet become effective. These securities may not be sold nor may offers to buy be accepted prior to the time the registration statement becomes effective. This press release shall not constitute an offer to sell or a solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

About Sharps Compliance Corp.

Headquartered in Houston, Texas, Sharps is a leading full-service provider of cost-effective disposal solutions for medical waste and unused dispensed medications generated outside the hospital and large healthcare facility setting. The Company's flagship product, the Sharps Disposal by Mail System(R), is a cost-effective and easy-to-use solution to dispose of medical waste such as hypodermic needles, lancets and any other medical device or objects used to puncture or lacerate the skin (referred to as "sharps").

Safe Harbor Statement

The information made available in this press release contains certain forward-looking statements which reflect Sharps Compliance Corp.'s current view of future events and financial performance. Wherever used, the words "estimate," "expect," "plan," "anticipate," "believe," "may" and similar expressions identify forward-looking statements. Any such forward-looking statements are subject to risks and uncertainties and the company's future results of operations could differ materially from historical results or current expectations. Some of these risks include, without limitation, the company's ability to educate its customers, development of public awareness programs to educate the identified consumer, customer preferences, the Company's ability to scale the business and manage its growth, the degree of success the Company has at gaining more large customer contracts, managing regulatory compliance and/or other factors that may be described in the company's annual report on Form 10-K, quarterly reports on Form 10-Q and/or other filings with the Securities and Exchange Commission. Future economic and industry trends that could potentially impact revenues and profitability are difficult to predict. The company assumes no obligation to publicly update or revise its forward-looking statements even if experience or future changes make it clear that any projected results express or implied therein will not be realized.

This news release was distributed by GlobeNewswire, www.globenewswire.com

SOURCE: Sharps Compliance, Inc.

CONTACT:  Sharps Compliance Corp.
David P. Tusa, Executive Vice President, Chief Financial
Officer & Business Development
(713) 660-3514
dtusa@sharpsinc.com
Kei Advisors LLC
Investor Relations
Deborah Pawlowski
(716) 843-3908
dpawlowski@keiadvisors.com

Expected next investor conference call information:
Conference Call Date: 10/27/2009
Conference Call Time (ET): 1:00 PM
Conference Call URL: http://www.sharpsinc.com/investorevents.htm

Expected next investor conference call information:
Conference Call Date: 10/27/2009
Conference Call Time (ET): 1:00 PM
Conference Call URL: http://www.sharpsinc.com/investorevents.htm

About Sharps Compliance Corp.

Headquartered in Houston, Texas, Sharps Compliance is a leading provider of cost-effective disposal solutions for medical and pharmaceutical waste generated outside the hospital setting. The Company's flagship product, the Sharps Disposal by Mail System(r), is a cost-effective and easy-to-use solution to dispose of medical waste such as hypodermic needles, lancets and any other medical device or objects used to puncture or lacerate the skin (referred to as "sharps").

The Sharps(r)MWMS(tm), a Medical Waste Management System, is a comprehensive medical waste solution which includes an array of services and products necessary to effectively collect, store and dispose of medical waste outside of the hospital setting. The System, which is designed for rapid deployment, features the Sharps Disposal by Mail System(r) products combined with warehousing, inventory management, training, data and other services necessary to provide a comprehensive solution. The Sharps(r)MWMS(tm) is designed to be an integral part of governmental and commercial emergency preparedness programs.

The Company also offers a number of products specifically designed for the home healthcare market and products for the safe disposal of unused pharmaceuticals, RxTakeAway(tm). Sharps Compliance focuses on targeted growth markets such as the pharmaceutical, retail, commercial, and hospitality markets, as well as serving a variety of additional markets. Sharps is a leading proponent and participant in the development of public awareness and solutions for the safe disposal of needles, syringes and other sharps as well as unused pharmaceuticals in the community setting.

As a fully integrated manufacturer providing customer solutions and services, Sharps Compliance's solid business model, with strong margins and significant operating leverage, and early penetration into emerging markets, uniquely positions the company for strong future growth.

More information on Sharps Compliance can be found on its website at: www.sharpsinc.com

This news release was distributed by GlobeNewswire, www.globenewswire.com

SOURCE: Sharps Compliance, Inc.

CONTACT:  Sharps Compliance Corp.
David P. Tusa, Executive Vice President, Chief
Financial Officer & Business Development
(713) 660-3514
dtusa@sharpsinc.com
Kei Advisors LLC
Investor Relations
Deborah Pawlowski
(716) 843-3908
dpawlowski@keiadvisors.com