The Sleuthing Behind Heparin

www.pharmamanufacturing.com | Sep 10, 2008

Early this year, as we all stood riveted and perplexed by the news that patients had died after receiving contaminated heparin, FDA and key members of the scientific community scrambled to find answers and uncover the roots of the tainted product.

http://www.pharmamanufacturing.com/articles/2008/117.html?CMP=ILC-rss

Researchers confirm heparin contaminant

uk.reuters.com | Apr 23, 2008

WASHINGTON (Reuters) - Researchers said they had identified a chemical contaminating the blood-thinner heparin from China, confirming U.S. Food and Drug Administration findings that it was oversulfated

http://uk.reuters.com/article/healthNews/idUKN2345672220080423?feedType=RSS&feedName=healthNews

Sulonex from Keryx: Unlikely Phase III Success

seekingalpha.com | Feb 27, 2008

Keryx Biopharmaceuticals' (KERX) Sulonex (sulodexide) is an orally available heparinoid (80% heparan sulfate, 20% dermatan sulfate) currently in phase III/IV trials for use in diabetic nephropathy.

http://seekingalpha.com/article/66186-sulonex-from-keryx-unlikely-phase-iii-success?source=feed

MedlinePlus Medical Encyclopedia: Scheie syndrome

Scheie syndrome is an inherited disease of metabolism in which the body cannot properly break down long chains of sugar molecules called glycosaminoglycans (formerly called mucopolysaccharides). The syndrome belongs to a group of diseases called mucopolysaccharidoses (MPS).

http://www.nlm.nih.gov/medlineplus/ency/article/001246.htm

Biomol - USBio: Human Protease Inhibitors

A2294-05 Angiostatin is a single-chain, proteolytic fragment of glu-plasminogen which has a molecular weight of about 38,000. It is a potent inhibitor of angiogenesis and was first identified and isolated from the serum and urine of tumor bearing mice.

http://www.biomol.de/infos_usbio.html?id=702&hersteller=USBio

ScienceDirect - Osteoarthritis and Cartilage, Articles in Press

www.sciencedirect.com

ScienceDirect - the world's leading platform offers over 2,000 high quality peer-reviewed full-text journals and books on science, technology and medicine.

https://www.sciencedirect.com/science?_ob=PublicationURL&_tockey=%23TOC%236979%239999%23999999999%2399999%23FLA%23&_cdi=6979&_pubType=J&view=c&_auth=y&_version=1&_urlVersion=0&_userid=10&md5=b631b035cf7610a5561d9176282f7e22

LEO Pharma.com - Drug Candidates to Clinical Trials

11-12-2001 Today, LEO and Canadian GlycoDesign Inc. announced their selection of anti-thrombotic drug candidates to move forward into clinical trials. The goal of the clinical program is to develop products for the treatment of venous thrombosis (e.g.

http://www.leo-pharma.com/41256A84002BE7FC/0/2E89B38220197F79C1256C440038315B?OpenDocument

Mucopolissacaridose I - Lipocondrodistrofia HONselect

A naturally occurring glycosaminoglycan found mostly in the skin and in connective tissue. It differs from CHONDROITIN SULFATE A (see CHONDROITIN SULFATES) by containing IDURONIC ACID in place of glucuronic acid, its epimer, at carbon atom 5.

http://www.hon.ch/HONselect/RareDiseases/PT/C16.320.565.202.715.640.html